Identification of a Risk Profile Associated with Failure of the Hybrid Ablation of Atrial Fibrillation.
Recruiting
- Conditions
- atrial fibrillation10007521
- Registration Number
- NL-OMON47743
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
Potential candidates for the study have agreed to undergo the hybrid AF
ablation procedure.
Exclusion Criteria
There are no specific exclusion criteria.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary outcome is failure of the hybrid AF ablation, i.e. any (a)symptomatic<br /><br>AF/AFL/AT >30 sec without anti-arrhythmic drugs determined at 1 year of<br /><br>follow-up by ECG recording and prolonged Holter monitoring.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes concern the identification of a risk profile associated with<br /><br>(long-term) failure or succes of the procedure, the number of patients<br /><br>requiring endocardial ablation in addition to epicardial ablation during the<br /><br>procedure, the electrophysiological findings (voltage, areas of fractionated<br /><br>potentials) during the procedure, the incidence and type of supraventricular<br /><br>tachyarrhythmias following the procedure, the changes in left atrial size and<br /><br>function, the use of anti-arrhythmic drugs, the frequency of repeated<br /><br>ablations, the quality of life and physical activity, and the adipose tissue<br /><br>biomarkers that are associated with the progression, prognosis and other<br /><br>markers of atrial fibrillation.</p><br>