NCT07304479招募中不适用
Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery on Airway Plateau Pressure: a Randomized, Prospective, Blinded Pilot Study
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- airway plateau pressure
研究概览
简要总结
Inhalational anesthetics, when used in abdominal surgery, offer advantages of lung protection and reduced alveolar inflammation. There is little literature, however, in the comparative use of sevoflurane versus desflurane anesthesia in patients undergoing abdominal robotic-assisted surgery and their effects on lung mechanics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 87 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 to 87 years
- •Undergoing elective robotic-assisted abdominal surgery
- •ASA physical status I-III
排除标准
- •ASA IV or V
- •Emergency surgery
- •Renal insufficiency
- •Clinically significant respiratory disease
- •Cardiomyopathy
- •Uncontrolled hypertension
研究组 & 干预措施
Sevoflurane (Volatile Anesthetic)
Active Comparator
干预措施: Sevoflurane (Volatile Anesthetic) (Drug)
Deslfurane (Volatile Anesthetic)
Active Comparator
干预措施: Desflurane (volatile anesthetic) (Drug)
结局指标
主要结局
airway plateau pressure
时间窗: Perioperatively
Airway plateau pressure (cmH2O) as displayed on the anesthesia ventilator at the specified time points will be recorded for each participant.
次要结局
未报告次要终点
研究者
Aliki Tympa
Assistant Professor of Anesthesiology
National and Kapodistrian University of Athens
研究点 (1)
Loading locations...
相似试验
Unknown
4 期
The Effect of Desflurane vs Sevoflurane on Perioperative Respiratory Complications in Laryngeal Mask Airway AnesthesiaLaryngeal MasksRespiratory System AbnormalitiesAdverse Effect AnesthesiaNCT03006250Chiang Mai University220
尚未招募
不适用
Evaluation of effect of anesthestic agents on the outcome of the patients sedule for brain tumor surgeryCTRI/2022/04/041940Health and family welfare department80
已完成
4 期
Inhalation anesthesia with sevoflurane vs intravenous anesthesia with propofol and dexmedetomidine on postoperative nausea vomiting and recovery parameters after anesthesiaCTRI/2023/08/057104Apollo Hospitals Bilaspur80
进行中（未招募）
1 期
Sevoflurane versus standard general anesthesia in elective open abdominal aortic aneurism surgeryAbdominal aortic aneurismMedDRA version: 18.0Level: PTClassification code 10002885Term: Aortic aneurysm repairSystem Organ Class: 10042613 - Surgical and medical proceduresEUCTR2014-004604-29-DKJens Rolighed Larsen24
招募中
不适用
Effects of sevoflurane anesthesia on intraoperative diastolic function: a randomized prospective observational studyDiseases of the circulatory systemKCT0002750Samsung Medical Center60