Collaborative care in screen-positive elders (CASPER) trial

Not Applicable

Completed

• Conditions: Mental and Behavioural Disorders; Sub-clinical depression; Depressive episode

• Registration Number: ISRCTN02202951
• Lead Sponsor: niversity of York (UK)

Brief Summary

2011 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/21988800 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26766034 2017 results in: http://www.ncbi.nlm.nih.gov/pubmed/28241357 2017 results in: http://www.ncbi.nlm.nih.gov/pubmed/28248154 2020 study within a trial (SWAT) results in https://pubmed.ncbi.nlm.nih.gov/32789011/ (added 17/08/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-03
• Study Completion: 2014-11-14
• Last Update Posted: 31 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 658

Inclusion Criteria

Inclusion criteria as of 10/03/2016:
1. Age = 75 years during the pilot phase or = 65 years during the main trial
2. Identified by a GP practice as being able to take part in collaborative care

Original inclusion criteria:
Elderly people (aged 75 years and older, either sex) with screen-positive depression on the Quality Outcomes Framework Depression 1 (QOF DEP1) - compliant 'two depression screening questions', but do not reach the threshold for International Classification of Disease, version 10 (ICD 10) moderate depressive disorder

Exclusion Criteria

Exclusion criteria as of 10/03/2016:
Those identified by a primary care clinician as:
1. Having a known alcohol dependency (as recorded on GP records)
2. Experiencing psychotic symptoms (as recorded on GP records)
3. Having any known comorbidity that would, in the GP’s opinion, make entry to the trial inadvisable (e.g. recent evidence of suicidal risk/self-harm, significant cognitive impairment)
4. Being affected by other factors that would make an invitation to participate in the trial inappropriate (e.g. recent bereavement, terminal malignancy)

Original exclusion criteria:
1. Reached threshold for ICD 10 moderate depressive disorder
2. Patients with alcohol dependence
3. Patients with dementia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Self reported depression severity (as measured by the 9-item Patient Health Questionnaire [PHQ-9]) at 4 months as a continuous measure.