NCT03370861Unknown不适用
Immunotherapy Multi-omics Specimen Protocol A
适应症
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 125
- 试验地点
- 1
- 主要终点
- Immune-related Adverse Events (irAEs)
研究概览
简要总结
The purpose of this research study is to examine the relationship between the microbiota (microscopic organisms) in the gut and the activity of the immune system during skin cancer immunotherapy.
详细描述
Details will be available upon publication.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥18 years of age.
- •Diagnosis of skin cancer.
- •Planning to initiate or already on ANY type of immunotherapy.
- •Able to provide urine and stool specimens.
排除标准
- •Bowel resection.
- •Major GI surgery in the past 5 years other than cholecystectomy and appendectomy.
结局指标
主要结局
Immune-related Adverse Events (irAEs)
时间窗: 2 years
Electronic medical records will be queried for specific drug-related adverse events known as immune-related Adverse Events (irAEs) including but not limited to colitis, hypophysitis, hepatitis, pneumonitis, pancreatitis, arthritis, rash, and vitiligo.
次要结局
- Overall Survival(2 years)
研究者
William H. McCoy IV, MD, PhD
Research Instructor of Medicine
Washington University School of Medicine
研究点 (1)
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