Towards eMTCT: Innovative strategies for improving mother-child pair retention and access to essential PMTCT care in Malawi

Not Applicable

Recruiting

• Conditions: HIV/AIDS

• Registration Number: PACTR201312000678196
• Lead Sponsor: College of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-10-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 2310

Inclusion Criteria

All HIV-positive pregnant women who attend antenatal clinics in the selected study health centers and babies born to them.

Exclusion Criteria

1.Those who not permanent residents of catchment villages surrounding the health facilities and who plan to move out of the catchment villages in the following 6-9 months.
2.Those who at the time of enrollment intend to relocate to other districts,
3.Those who cannot independently give informed consent because of immediate life¿threatening illness or mental disorders.
4.Those who did not receive ANC care, including the initial visit, at the randomized health centers or received their first HIV test in the postnatal period. This is to make sure that we are assessing retention of the mother¿infant pairs from the first point of entry into the PMTCT cascade.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of HIV-exposed infants retained in HIV care and treatment at 12 months postpartum;Proportion of HIV-positive women retained in care and treatment (Option B+ regimen) at 12 months postpartum.

Secondary Outcome Measures

Name	Time	Method
Proportion of HIV-exposed infants who have received HIV DNA PCR test by 2 months of age and received results;Proportion of HIV exposed infants receiving all cotrimoxazole refills from 6 weeks to 6 months of age;Mean number of scheduled visits made by mother and infant from first ANC visit to 12 months postpartum.;Proportion of HIV-exposed infants retained in care and treatment at 24 months postpartum.;Proportion of women alive and on Option B+ ART regimen at 24 months postpartum;Cost per Mother Infant Pair (MIP) retained at 12 months of age;Cost per early infant diagnosis test (HIV DNA PCR) result received.;Cost per infant initiated on ART