The effect of a Mediterranean Diet, with adequate dairy foods, to meet Australian recommendations, on cardiometabolic and cognitive health outcomes in men and women at high risk of cardiovascular disease.

Dr Karen Murphy0 个研究点目标入组 39 人开始时间: 2016年3月9日最近更新: 2020年1月13日

试验速览

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•Free-living non-smoking men and women aged between 45 to 75 years with elevated systolic BP between 120mmHg and 140mmHg (high-normal range) and not on antihypertensive medication
•with at least 2 risk factors for cardiovascular disease (CVD):
•overweight/obese with body mass index 25kg/m2 or above
•waist circumference men >94cm, women >80cm
•dyslipidemia one of the following (fasted) : total cholesterol 5.5mM or above, triglycerides 2.0mM or above, low density lipoprotein cholesterol (LDL) 3.5 or above, high density lipoprotein cholesterol (HDL) men 0.9 and women 1.0 or below,
•impaired glucose tolerance (fasting glucose <7.0mmol/L)
•family history of CVD (myocardial infarction or sudden death before 55yrs for men or 65yrs for female 1st degree relatives)
•Family history of type 2 diabetes mellitus (T2DM)

•Person considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol
•Previous/current traumatic head/brain injury, neurological or psychiatric conditions
•Previous stroke
•Use of anti-depressant, anxiety or neurological or psychiatric medication
•Current or recent (in the last 6 months) malignancy
•Major liver, kidney, respiratory, gastrointestinal disease
•Current CVD or angina
•Actively trying to lose weight
•Pregnancy/lactating
•Diagnosed T2DM
•Allergy/sensitivity to nuts, seafood, dairy foods etc.
•Illegal drug use or alcoholism
•Weight >135kg (DEXA limitations)
•Diagnosis of Alzheimer’s disease or dementia

发起方

Dr Karen Murphy