The effect of a Mediterranean diet with adequate dairy foods on cardio-metabolic and cognitive health outcomes

Not Applicable

Completed

• Conditions: Cardiovascular health; Cardiometabolic health; Wellbeing and cognitive performance; Diet and Nutrition - Other diet and nutrition disorders; Cardiovascular - Hypertension; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12616000309482
• Lead Sponsor: Dr Karen Murphy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

Free-living non-smoking men and women aged between 45 to 75 years with elevated systolic BP between 120mmHg and 140mmHg (high-normal range) and not on antihypertensive medication
with at least 2 risk factors for cardiovascular disease (CVD):
overweight/obese with body mass index 25kg/m2 or above
waist circumference men >94cm, women >80cm
dyslipidemia one of the following (fasted) : total cholesterol 5.5mM or above, triglycerides 2.0mM or above, low density lipoprotein cholesterol (LDL) 3.5 or above, high density lipoprotein cholesterol (HDL) men 0.9 and women 1.0 or below,
impaired glucose tolerance (fasting glucose <7.0mmol/L)
family history of CVD (myocardial infarction or sudden death before 55yrs for men or 65yrs for female 1st degree relatives)
Family history of type 2 diabetes mellitus (T2DM)

Exclusion Criteria

Person considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol
Previous/current traumatic head/brain injury, neurological or psychiatric conditions
Previous stroke
Use of anti-depressant, anxiety or neurological or psychiatric medication
Current or recent (in the last 6 months) malignancy
Major liver, kidney, respiratory, gastrointestinal disease
Current CVD or angina
Actively trying to lose weight
Pregnancy/lactating
Smoker
Diagnosed T2DM
Allergy/sensitivity to nuts, seafood, dairy foods etc.
Illegal drug use or alcoholism
Weight >135kg (DEXA limitations)
Diagnosis of Alzheimer’s disease or dementia

Study & Design

• Study Type: Interventional
• Study Design: Not specified