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Genotoxicity with the use of fixed orthodontic appliances and folic acid

Not Applicable
Conditions
Healthy teenagers and adults
Registration Number
JPRN-UMIN000053676
Lead Sponsor
Center for Research and Advanced Studies in Dentistry "Dr. Keisaburo Miyata" (C.I.E.A.O.), Faculty of Dentistry, UAEMex
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

1. Pregnant women 2. Patients with cancer or taking antineoplastics

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Frequency of micronuclei and nuclear abnormalities in patients with orthodontic fixed appliances and folic acid intake
Secondary Outcome Measures
NameTimeMethod
Frequency of micronuclei and nuclear abnormalities in three groups: control, patients with orthodontic fixed appliances, and patients with orthodontic fixed appliances and folic acid intake in a six-month period
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