Optimizing Exposure Therapy for Posttraumatic Stress Disorder
- Conditions
- Posttraumatic stress disorder
- Registration Number
- NL-OMON20527
- Lead Sponsor
- eiden University, Institute of Psychology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 180
In order to be eligible to participate in this study, a participant must meet all of the following criteria:
• Diagnosed with current PTSD and satisfying DSM-5 defined criteria for Post-Traumatic
Stress Disorder as established by SCID-5-SV interview
• Self-reported PTSD symptoms above clinical cut-off (i.e. PCL-5 score > 31)
• Index trauma is related to physical or sexual violence
• One specific memory related to the index trauma
• Age between 18 and 70 years
A potential participant who meets any of the following criteria will be excluded from participation in this study:
• Current trauma-focused treatment (e.g. exposure; EMDR)
• Patients with significant suicidal ideations/serious self-injurious behaviour or who have enacted suicidal behaviours or serious self-injurious behaviour within 3 months prior to intake will be excluded from participation
• Mental retardation
• Substance or alcohol dependence
• Somatic illness that interfere with exposure interventions or planned assessments (e.g. cardiac conditions)
• Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main outcome will be change from baseline to one week follow-up in subjective fear (i.e. Subjective Units of Distress; SUDs) and physiological fear responses (i.e. heart rate and skin conductance) during a trauma imagery procedure.
- Secondary Outcome Measures
Name Time Method Secondary study outcomes will be change from baseline to one week follow-up in avoidance behaviour and self-reported PTSD symptoms over the past week.