Physiological and Biochemical Effects of Laparoscopic Anesthesia and Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anesthesia Complication
- Sponsor
- Mohammed Abdulhameed
- Enrollment
- 60
- Primary Endpoint
- blood sugar, should measured and assessed with different groups
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
Laparoscopic surgery is widely used now. These benefits included many items, e.g. reducing post-operative pain, cosmetic the result was improved, and the patient also had more satisfaction for the patient and reduced hospital stay. This surgery involved insufflation of gas into the peritoneal cavity, producing pneumoperitoneum, and causing an increase in intra-abdominal pressure. The raised intraabdominal pressure of the pneumoperitoneum, the patient's position alteration, and the absorption of carbon dioxide into the abdomen have a direct effect on causing a change in physiology, especially in the cardiovascular and respiratory systems. These effects, as well as a direct effect of gas insufflation, may have significant effects on the patient especially if the patient has a comorbidity or is elderly.
Detailed Description
The objective of this study was to assess the technique used in laparoscopic surgery and their associated complications, including some hematological parameters, (these include blood pictures and liver enzymes), respiratory, (including the inspired and expired tidal volume, oxygen saturation, airway pressure, plateau pressure, and use of PEEP) cardiovascular system (including the systolic, diastolic, and mean blood pressure, heart rate)
Investigators
Mohammed Abdulhameed
principal investigator
Tunis University
Eligibility Criteria
Inclusion Criteria
- •elective abdominal surgery
- •a healthy, fit person
- •use of general anesthetics
- •use of pneumoperitoneum and CO2 insufflation
Exclusion Criteria
- •emergency condition
- •patient with cardiovascular disease
Outcomes
Primary Outcomes
blood sugar, should measured and assessed with different groups
Time Frame: 5 minute during pre-operative and 15 minute post- operative period
blood sugar in mg/dl
end-tidal Co2, measured and compared statistically with other parameter
Time Frame: perioperatively every 5 minute
End-tidal Co2 in CMH2O
blood pressure.
Time Frame: during preoperative, 5 minute, intraoperative every five minute with post operative read after one hour
blood pressure in mmHg, pulse rate in beat per minute
AST and ALT liver enzymes were measured, by blood samples taken intravenously in the perioperative period
Time Frame: 5 minute pre-operation and 5 minute postoperative
in unit/liter
pulse rate measured continuously during intra-operative and compared with other hemodynamic parameter
Time Frame: 5 minute during preoperative, and continue every 5 minute in perioperatively
beat per minute (BPM)
Secondary Outcomes
- measurement of body weight(measured preoperative period by 5 minute and post-operative during 15 minute)