This Study Assess Some Physiological Parameters, Blood Picture, and Hemodynamic Parameters, Blood Pressure, Respiratory Assess by SPO2, During Different Periods in Laparoscopic Surgery

Not Applicable

Not yet recruiting

• Conditions: Physiological Parameter; Anesthesia Complication
• Interventions: Procedure: general anesthesia drug (like Propofol, esmeron, and ketamin, .effects of pneumoperitoneum

• Registration Number: NCT06473194
• Lead Sponsor: Mohammed Abdulhameed

Brief Summary

Laparoscopic surgery is widely used now. These benefits included many items, e.g. reducing post-operative pain, cosmetic the result was improved, and the patient also had more satisfaction for the patient and reduced hospital stay. This surgery involved insufflation of gas into the peritoneal cavity, producing pneumoperitoneum, and causing an increase in intra-abdominal pressure. The raised intraabdominal pressure of the pneumoperitoneum, the patient's position alteration, and the absorption of carbon dioxide into the abdomen have a direct effect on causing a change in physiology, especially in the cardiovascular and respiratory systems. These effects, as well as a direct effect of gas insufflation, may have significant effects on the patient especially if the patient has a comorbidity or is elderly.

Detailed Description

The objective of this study was to assess the technique used in laparoscopic surgery and their associated complications, including some hematological parameters, (these include blood pictures and liver enzymes), respiratory, (including the inspired and expired tidal volume, oxygen saturation, airway pressure, plateau pressure, and use of PEEP) cardiovascular system (including the systolic, diastolic, and mean blood pressure, heart rate)

Study Timeline

• Status Verified: 2024-06
• Study First Submitted: 2024-06-01
• Study First Submitted QC: 2024-06-21
• Last Update Submitted: 2024-06-21
• Study First Posted: 2024-06-25
• Last Update Posted: 2024-06-25
• Study Start: 2024-10-01
• Primary Completion: 2026-10-01
• Study Completion: 2026-11-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. elective abdominal surgery
2. a healthy, fit person
3. use of general anesthetics
4. use of pneumoperitoneum and CO2 insufflation

Exclusion Criteria

1. emergency condition
2. patient with cardiovascular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
age , gender	general anesthesia drug (like Propofol, esmeron, and ketamin, .effects of pneumoperitoneum	group according to age and according to gender

Primary Outcome Measures

Name	Time	Method
blood sugar, should measured and assessed with different groups	5 minute during pre-operative and 15 minute post- operative period	blood sugar in mg/dl
end-tidal Co2, measured and compared statistically with other parameter	perioperatively every 5 minute	End-tidal Co2 in CMH2O
blood pressure.	during preoperative, 5 minute, intraoperative every five minute with post operative read after one hour	blood pressure in mmHg, pulse rate in beat per minute
AST and ALT liver enzymes were measured, by blood samples taken intravenously in the perioperative period	5 minute pre-operation and 5 minute postoperative	in unit/liter
pulse rate measured continuously during intra-operative and compared with other hemodynamic parameter	5 minute during preoperative, and continue every 5 minute in perioperatively	beat per minute (BPM)

Secondary Outcome Measures

Name	Time	Method
measurement of body weight	measured preoperative period by 5 minute and post-operative during 15 minute	in Kg