Enhanced Recovery After Surgery Protocol in Laparoscopic Surgery for Colorectal Cancer: Risk Factors for Delayed Recovery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 143
- 试验地点
- 1
- 主要终点
- Hospital length of stay (days)
研究概览
简要总结
Although there is evidence for reducing complication rate and improving recovery after the implementation of Enhanced Recovery After Surgery (ERAS) protocols into colorectal surgery, most published papers include patients undergoing open resections. The aim was to analyse factors affecting recovery and length of stay (LOS) in patients after laparoscopic colorectal surgery for cancer combined with ERAS protocol.
详细描述
All patients were operated using laparoscopic surgery, and the perioperative care was based on pre-established ERAS protocol consisting of 13 pre and intraoperative items. Its principles and criteria for discharge from the hospital were based on the ERAS Society Guidelines.
Investigators analysed which of the factors: gender; age; BMI; ASA (American Society of Anaesthesiologists) physical status; type of surgery (colonic resection vs. rectal resection with total mesorectal excision, TME); stage of cancer; distance between the hospital and place of residence; operative time; intraoperative blood loss significantly prolong LOS (primary length of stay, excluding readmissions). Moreover, the compliance with ERAS protocol and its influence on LOS was analysed.
For the purposes of further analyses the entire group of patients was divided into 2 subgroups depending on the length of their hospital stay. On admission every patient received the information about the target length of stay of 4 days. Group 1 consisted of patients whose hospital stay was shorter or equal to the target LOS (≤ 4 days). In group 2 were patients whose hospital stay was longer than 4 days.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •colorectal cancer
- •laparoscopic resection
- •perioperative care according to ERAS principles
排除标准
- •Patients submitted initially for open or emergency surgery
- •with complex cancer who required multi-organ resection
- •patients treated with endoscopic techniques using the hybrid TaTME technique (Transanal Total Mesorectal Excision)
结局指标
主要结局
Hospital length of stay (days)
时间窗: participants will be followed for the duration of hospital stay, an expected average of 4 days
次要结局
- Compliance with ERAS protocol (%)(participants will be followed for the duration of hospital stay, an expected average of 4 days)
- Complication rate (%)(up to 30 days post surgery)
- Readmission rate (%)(up to 30 days post surgery)
研究者
Michał Pędziwiatr
Michał Pędziwiatr, MD PhD
Jagiellonian University