Coronary Calcium Scoring Versus Standard Care for Emergency Department Chest Pain Patients

Not Applicable

Withdrawn

• Conditions: Chest Pain
• Interventions: Device: Coronary Calcium Scoring; Procedure: Standard Care

• Registration Number: NCT02828761
• Lead Sponsor: Montefiore Medical Center

Brief Summary

This research asks whether coronary calcium scoring, a non-invasive test based on computed tomography scanning, is a better way to diagnose chest pain patients than other currently used methods. Three of four patients will undergo calcium scoring and the remaining patients will receive standard care.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-06-15
• Study First Submitted QC: 2016-07-07
• Study First Posted: 2016-07-12
• Study Start: 2023-07
• Status Verified: 2023-09
• Primary Completion: 2023-09-14
• Study Completion: 2023-09-14
• Last Update Submitted: 2023-09-14
• Last Update Posted: 2023-09-15

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• complaint of chest pain or pressure
• intermediate risk by HEART score
• clinical indication for non-invasive cardiac imaging
• free of known coronary artery disease

Exclusion Criteria

• hemodynamic instability
• electrocardiogram suggestive of acute ischemia or myocardial infarction
• unremitting chest pain
• serum troponin levels greater than three times the laboratory threshold
• unable to give his/her own written, informed consent
• pregnant women
• weight > 182 kg
• unable to lie supine for scan
• coronary calcium score, coronary CTA or non-contrast thoracic CT within the last year and available for review
• unable to comply with 30 day follow-up

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Coronary Calcium Scoring	Coronary Calcium Scoring	Coronary calcium scoring by multidetector row computed tomography (MDCT).
Standard Care	Standard Care	Standard evaluation of chest pain patient which often includes immediate non-invasive imaging.

Primary Outcome Measures

Name	Time	Method
Major Adverse Cardiovascular Events	30 days	number of patients with death, non-fatal heart attack, non-fatal stroke, non-fatal cardiac arrest

Secondary Outcome Measures

Name	Time	Method
Length of Stay	through completion of emergency department stay for each patient, an average of six hours and through completion of hospitalization, an average of two days	emergency department and inpatient

Trial Locations

Locations (2)

Montefiore Medical Center - Einstein Division; 🇺🇸 Bronx, New York, United States

Montefiore Medical Center - Wakefield Division; 🇺🇸 Bronx, New York, United States