A Randomized Controlled Trial Comparing Coronary CT Angiography and Radionuclide Stress Myocardial Perfusion Imaging in Symptomatic Inpatients With Known Coronary Artery Disease

Montefiore Medical Center1 site in 1 country7 target enrollmentApril 2010

ConditionsCoronary Artery Disease Angina Pectoris Unstable Angina Acute Coronary Syndrome

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Coronary Artery Disease
Sponsor: Montefiore Medical Center
Enrollment: 7
Locations: 1
Primary Endpoint: Number of participants that undergo subsequent cardiac catheterization but do not have consequent coronary angioplasty, stenting or bypass
Status: Terminated
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether coronary artery CT scanning or nuclear stress testing is better at diagnosing chest pain patients with known coronary artery disease to select appropriate candidates for coronary catheterization and re-vascularization.

Registry

clinicaltrials.gov

Start Date

April 2010

End Date

December 2013

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Montefiore Medical Center

Responsible Party

Principal Investigator

Jeffrey Levsky

Associate Director of Research

Montefiore Medical Center

Eligibility Criteria

Inclusion Criteria

•patient admitted for chest pain / pressure or other suggestive symptoms
•patient has known coronary artery disease (with or without prior revascularization)
•patient has clinical need for non-invasive cardiac evaluation

Exclusion Criteria

•evidence of ongoing myocardial infarction or hemodynamic instability
•ischemia on EKG (greater than 1mm ST segment deviation)
•contraindications to CT scanning with iodinated intravenous contrast (including allergies, asthma and renal dysfunction)
•heart rhythm precluding EKG gating
•pregnancy

Outcomes

Primary Outcomes

Number of participants that undergo subsequent cardiac catheterization but do not have consequent coronary angioplasty, stenting or bypass

Time Frame: 3 months

Secondary Outcomes

Length of hospital stay (time to discharge)(1 month)
Number of participants that have a subsequent non-fatal myocardial infarction(1 year)
Number of participants that experience a procedural complication due to non-invasive imaging, cardiac catheterization or coronary revascularization(3 months)
Number of participants that die due to any cause(1 year)