A Randomized Trial Comparing Coronary CT Angiography and Stress Echocardiography for Evaluation of Low-to-Intermediate Risk Emergency Department Chest Pain Patients

Montefiore Medical Center1 site in 1 country400 target enrollmentAugust 2011

ConditionsChest Pain Angina Angina Pectoris Coronary Artery Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Chest Pain
Sponsor: Montefiore Medical Center
Enrollment: 400
Locations: 1
Primary Endpoint: Hospital admission
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether stress echocardiography or computed tomography (CT) of the heart is better at diagnosing emergency room chest pain patients to select appropriate candidates for hospitalization and further work-up.

Registry

clinicaltrials.gov

Start Date

August 2011

End Date

February 2017

Last Updated

7 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Montefiore Medical Center

Responsible Party

Principal Investigator

Jeffrey Levsky

Associate Director of Research, Department of Radiology

Montefiore Medical Center

Eligibility Criteria

Inclusion Criteria

•Presentation to the Emergency Department with chest pain
•Low-to-intermediate risk of coronary disease per Diamond-Forrester criteria
•Free of known coronary artery disease

Exclusion Criteria

•Inability to undergo both stress echo or coronary CT for any reason
•Contraindication to intravenous iodinated contrast
•Dysrhythmia precluding EKG gating
•Heart rate greater than 60 with contraindication to beta blockers
•Administration of beta blockers within the last 12 hours
•Known severe cardiac valvular disease or pulmonary hypertension
•Stress echocardiography, coronary CT or catheterization within the last 6 months