NCT01106612终止不适用
A Randomized Controlled Trial Comparing Coronary CT Angiography and Radionuclide Stress Myocardial Perfusion Imaging in Symptomatic Inpatients With Known Coronary Artery Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 7
- 试验地点
- 2
- 主要终点
- Number of participants that undergo subsequent cardiac catheterization but do not have consequent coronary angioplasty, stenting or bypass
研究概览
简要总结
The purpose of this study is to determine whether coronary artery CT scanning or nuclear stress testing is better at diagnosing chest pain patients with known coronary artery disease to select appropriate candidates for coronary catheterization and re-vascularization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient admitted for chest pain / pressure or other suggestive symptoms
- •patient has known coronary artery disease (with or without prior revascularization)
- •patient has clinical need for non-invasive cardiac evaluation
排除标准
- •evidence of ongoing myocardial infarction or hemodynamic instability
- •ischemia on EKG (greater than 1mm ST segment deviation)
- •contraindications to CT scanning with iodinated intravenous contrast (including allergies, asthma and renal dysfunction)
- •heart rhythm precluding EKG gating
- •pregnancy
研究组 & 干预措施
Initial coronary CT angiography
Experimental
EKG-gated, computed tomography angiography of the coronary arteries during heart rate control
干预措施: Coronary CT angiography (Procedure)
Initial nuclear stress test
Active Comparator
Stress radionuclide myocardial perfusion imaging
干预措施: Myocardial perfusion imaging (Procedure)
结局指标
主要结局
Number of participants that undergo subsequent cardiac catheterization but do not have consequent coronary angioplasty, stenting or bypass
时间窗: 3 months
次要结局
- Length of hospital stay (time to discharge)(1 month)
- Number of participants that have a subsequent non-fatal myocardial infarction(1 year)
- Number of participants that experience a procedural complication due to non-invasive imaging, cardiac catheterization or coronary revascularization(3 months)
- Number of participants that die due to any cause(1 year)
研究者
Jeffrey Levsky
Associate Director of Research
Montefiore Medical Center
研究点 (2)
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