To study the effects of different types of anesthesia management on lung and kidney functions after lung cancer surgery
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/10/046186
- Lead Sponsor
- Department of OncoAnaesthesia and Palliative Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Adult patients (age >18 years) of either sex, belonging to ASA class I -III, undergoing elective unilateral thoracotomies for lung resection surgeries within the study period in the Department of Onco-Anaesthesia and Palliative Medicine at the B R Ambedkar Institute Rotary Cancer Hospital (BRAIRCH), All India Institute of Medical Sciences (AIIMS), New Delhi
Patients with unoptimized mechanical or parenchymal lung diseases including pulmonary hypertension (pre-operative FEV1 < 50% of predicted value)
Patients with active infections – systemic or local
Patients with hemoglobin < 10g% or Serum albumin < 3 g/dL, pre-operatively
Patients who are allergic to any of the study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of post-operative pulmonary complicationsTimepoint: The post-operative period till discharge
- Secondary Outcome Measures
Name Time Method Any specific adverse event within the duration of hospital stayTimepoint: Post-operatively till discharge;Duration of mechanical ventilation and oxygen therapyTimepoint: Post-operatively till discharge;Length of hospital stayTimepoint: Post-operatively till discharge;Length of ICU stayTimepoint: Post-operatively till discharge;The incidence of AKI post-operatively (including the need for RRT)Timepoint: Post-operatively till discharge;The requirement of vasopressors (with dose) and inotropesTimepoint: Intra-operative period;The total amount of fluid infused with sub-classification into total amounts of crystalloids, colloids and blood products infusedTimepoint: Intra-operative period