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临床试验/CTRI/2024/10/075683
CTRI/2024/10/075683尚未招募不适用

Correlation of Cardiac Output measured by transpulmonary thermodilution versus Pulse Contour analysis in Liver transplant recipients

Amrita Institute Of Medical Sciences1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年11月14日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
试验地点
1
主要终点
Comparison of cardiac output measured by PiCCO thermodilution versus pulse contour during liver transplant surgery

研究概览

简要总结

Thermodilution and pulse contour are both the principles in PiCCO derived cardiac output.

PiCCO is more reliable and also provides parameters of lung water and global end diastolic volume that correlate with the volume status  and. are additional parameters

The study aims to look at the correlation of cardiac output measured by thermodilution with the pulse contour method and at the accuracy of PiCCO parameters global end-diatolic volume index and extra vascular lung water index with static parameters like the CVP and the oxygenation index

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 72.00 Year(s)(—)
性别
All

入选标准

  • All adult patients presenting for elective liver transplantation.

排除标准

  • Emergency transplants Transplants for acute liver failure and acute on chronic liver failure Multiorgan transplants.

结局指标

主要结局

Comparison of cardiac output measured by PiCCO thermodilution versus pulse contour during liver transplant surgery

时间窗: Specified times during surgery | T0 baseline | T1 2 h in the dissection phase | T2 Anhepatic phase after portal vein shunt | T3 10 minutes after reperfusion | T4 Skin closure at the completion of surgery

次要结局

  • Comparison of Global end diastolic volume index versus central venous pressure(Extravascular lung water index versus oxygenation index)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Lakshmi Kumar

Amrita Institute of Medical Sciences

研究点 (1)

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