Transpulmonary Thermodilution Measurements in Patients With Heart Diseases
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Heart Diseases
- Sponsor
- University of Zurich
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Cardiac Output, Preload values (GEDV)
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to examine the validation of the PiCCO (Pulse Contour Cardiac Output)-derived transpulmonary thermodilution technology in patients with heart diseases.
Detailed Description
* How do PiCCO and PAC (pulmonary artery catheter) derived hemodynamic variables change in different cardiac pathologies? * How do PiCCO hemodynamic variables compare to transthoracic echocardiographic parameters in different cardiac pathologies? * How does GEDV (global enddiastolic volume) correlate with left ventricles end-diastolic volume (LVEDV) assessed by LV (left ventricle) ventriculography and echocardiography? * How do PiCCO cardiac function variables (GEF \[global ejection fraction\]; CFI \[cardiac function index\]) correlate with LV dP/dt max, LVEF (left ventricular ejection fraction) assessed by LV ventriculography and echocardiography, LVFAC (left ventricular fractional area of change), LV stroke work index (LVSWI) and cardiac power (CP)? * How does GEDV compare to LVEDV and left ventricular end-diastolic pressure (LVEDP) as assessed by the pulmonary artery occlusion pressure (PAOP)? * How does right ventricular function influence GEDV, GEF and CFI?
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Cardiac Output, Preload values (GEDV)
Time Frame: Day 1 only
Outcome measure is obtained during PiCCO measurement and left/right heart catherization, respectively ("point-of-care" measurement). There is no follow-up examination thereafter.