Single Transpulmonary Thermodilution and Continuous Monitoring of Central Venous Oxygen Saturation During Off-pump Coronary Surgery

Not Applicable

Completed

• Conditions: Goal Directed Therapy; Coronary Artery Disease; Hemodynamic Monitoring
• Interventions: Device: Conventional monitoring; Device: Advanced monitoring

• Registration Number: NCT00624494
• Lead Sponsor: Northern State Medical University

Brief Summary

The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen saturation (ScvO2) for perioperative management of patients undergoing OPCAB.

Detailed Description

At the present time, there is an increasing tendency to perform off-pump coronary artery bypass grafting (OPCAB). However, OPCAB poses a variety of challenges from the point of view of the anesthesiologist and the intensivist. The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen saturation (ScvO2) for perioperative management of patients undergoing OPCAB.

Study Timeline

• Study Start: 2005-05
• Study First Submitted: 2008-02-13
• Study First Submitted QC: 2008-02-26
• Study First Posted: 2008-02-27
• Primary Completion: 2008-08
• Study Completion: 2008-09
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-20
• Last Update Posted: 2024-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients with coronary artery disease, ranked ASA II-III and scheduled for elective OPCAB

Exclusion Criteria

• Age < 18 years
• Severe valve dysfunction or peripheral vascular disease
• Simultaneous interventions (carotid endarterectomy, aneurysm repair, etc.)
• Transfer to CPB during surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional monitoring	Conventional monitoring	hemodynamic monitoring - conventional monitoring
Advanced monitoring	Advanced monitoring	hemodynamic monitoring - advanced monitoring

Primary Outcome Measures

Name	Time	Method
length of hospital stay	one month	Length of the hospital stays, Days

Trial Locations

Locations (1)

Dep. of Anesthesiology, Northern SMU; 🇷🇺 Arkhangelsk, Russian Federation