Improving Adherence to Medication in Stroke Survivors

Completed

Conditions: Stroke/transient ischaemic attack
Circulatory System
Transient cerebral ischaemic attacks and related syndromes

Registration Number: ISRCTN38274953

Lead Sponsor: niversity of Stirling (UK)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 60

Inclusion Criteria

1. Male and female patients who have suffered first-time stroke (ischaemic and haemorrhagic) or transient ischaemic attack (TIA)
2. Age range 18 + years (no upper age range)
3. Discharged from the Edinburgh Western General Hospital stroke units and clinics
4. Prescribed secondary antihypertensive medication on discharge
5. Exhibiting sub-optimal adherence on the Medication Adherence Report Scale (score of 24 or less)
6. Living at home
7. Responsible for own medication

Exclusion Criteria

1. Age below 18 years
2. Marked cognitive impairment (Mini-Mental State Examination [MMSE] less than 23)
3. Significant dysphasia (Frenchay screen greater than 13/20)
4. Already using Dosette boxes (or similar) to improve their medication adherence
5. Participants who are not responsible for their own medication

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Medication adherence recorded using MEMS (Medication Event Monitoring System, MEMS® Aardex Ltd, Switzerland) pill containers which electronically record openings. We shall use the following main outcomes, counting each opening as a presumptive dose:<br>1. Percentage of doses taken<br>2. Percentage of days on which the correct number of doses was taken<br>3. Percentage of doses taken on schedule

Secondary Outcome Measures

Name	Time	Method
1. MARS self-reported adherence of all secondary preventative medication<br>2. Systolic and diastolic blood pressure<br><br>Recorded at baseline and 3-month follow-up.