NCT00630006Unknown不适用
Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease
适应症
试验速览
- 阶段
- 不适用
- 试验地点
- 2
- 主要终点
- cytokine gene polymorphism
研究概览
简要总结
The prognosis of chronic hepatitis C virus (HCV)infeciton varies from minimal progressive disease to cirrhosis or hepatocellular carcinoma. Host genetic factors contribute to disease severity. It is known that cytokine gene (including tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) polymorphism affect disease prognosis.This study aims to assess the effect of TNF-alpha and IL-10, and their interaction,on prognosis of HCV-related chronic liver disease
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Anti-HCV-positive patients
排除标准
- •Anti-HCV-negative patients
结局指标
主要结局
cytokine gene polymorphism
时间窗: years
次要结局
- cytokine gene polymorphism on severity of disease(years)
研究者
研究点 (2)
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