Is movement direction encoding in the motor cortex determined by movement direction perse or muscle selection? An EMG-fMRI study in healthy subjects
Completed
- Conditions
- gezonde motoriekmotor organization
- Registration Number
- NL-OMON37287
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- between 18-30 years old
- right handed
- in good (subjective) health
- normal or corrected to normal vision
- informed consent
Exclusion Criteria
- history of epileptic seizures, head injury, neurological diseases or psychiatric diseases
- rheumatoid or other affliction affecting normal smooth movement of the wrist
- any history of orthopaedic treatment for wrist fracture
- use of any type of medication affecting the central or peripheral nervous system
- MR exclusion criteria:
- metal implants
- electronic implants (e.g. heart pacemaker) and connectors of electronic devices (e.g. implanted electrodes)
- claustrophobia
- pregnancy
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Activations in M1 related to the same wrist movement directions but starting<br /><br>from two distinct wrist positions requiring different muscle synergies, as<br /><br>determined by event-related fMRI analysis.</p><br>
- Secondary Outcome Measures
Name Time Method <p>NA</p><br>