Effect of electro-acupuncture on uterine blood flow characteristics in patients with recurrent implantation failure

Phase 1

• Conditions: recurrent implantation failure

• Registration Number: ITMCTR2200005690
• Lead Sponsor: Chengdu Xinan Gynecological Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

(1) Aged between 22 to 40 female.
(2) Meeting the diagnostic criteria for recurrent implantation failure.
(3) The availability of frozen embryos and prepare for FET .
(4) Patients undergoing endometrial preparation using a hormone replacement therapy or Gnrh-a down regulation hormone replacement therapy.
(5)Patients with endometrial flow type II or type I.
(6) Signed an informed consent form.
Note: Patients meeting all 6 criteria above were included in this study.

Exclusion Criteria

(1) Ultrasound examination shows unaddressed uterine malformations that clearly affect uterine morphology, uterine fibroids that compress the uterine cavity, or ovarian cysts
(2) Having a clearly diagnosis autoimmune disease or pre-thrombotic state, such as systemic lupus erythematosus, rheumatoid arthritis, etc.
(3) Having an unsolved endocrine disorder, such as hyperthyroidism, diabetes mellitus, hypertension, etc.
(4) Suffering from a clearly diagnosed medical or surgical serious primary or secondary disease or psychiatric disorder in progress.
(5) Patients with chromosomal abnormalities(Except for chromosome polymorphism).
(6) The patient has a history of assisted reproduction live births
(7) Patients with bleeding tendencies and those prone to infection, or those suffering from severe allergies, or with skin ulcers or scarring that prohibit needling or dizziness.
(8) Patients who have received acupuncture treatment in the last three months.
(9) Patients who are participating in other clinical trials.
Note: Anyone who meets any 1 of the above criteria will be excluded.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified