Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases
- Conditions
- Oral Lichen Planus
- Interventions
- Other: no intervention
- Registration Number
- NCT05403216
- Lead Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
- Brief Summary
On the basis of previous studies, a validation cohort will be established to explore the relationship between oral lichen planus and autoimmune thyroid diseases, and a disease efficacy prediction strategy can be formed.
- Detailed Description
For oral lichen planus patients, the prevalence of Hashimoto's thyroiditis will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
Besides, for patients with Hashimoto's thyroiditis, the prevalence of oral lichen planus will be investigated and the relationship between levels of anti-TG, anti-TPO antibodies and severity of oral lichen planus will be determined.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- OLP patients without systemic disease
- OLP patients with severe periodontal disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description OLP(+) no intervention OLP with positive thyroid antibody group
- Primary Outcome Measures
Name Time Method Oral lichen planus (OLP) lesions record 1 year Record changes of lesions based on the symptoms and signs of the oral lichen planus patient.
Level of thyroid function and antibody 1 year The levels of thyroid hormone and thyroid autoantibodies in serum of OLP patients were detected.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Stomatology Hospital, Zhejiang University School of Medicine
🇨🇳Hangzhou, Zhejiang, China