A Longitudinal Study on Adipose Tissue Distribution, Its Changes Following a Structured Exercise Program and Its Correlation with Disease Activity in Rheumatoid Arthritis.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 102
- 试验地点
- 1
研究概览
简要总结
This study is a longitudinal investigation designed to evaluate adipose tissue distribution and its changes following a structured exercise program in patients with rheumatoid arthritis. The study aims to assess the relationship between visceral and subcutaneous adipose tissue and disease activity, inflammation, and functional outcomes over a six month period. Participants will receive standard medical care along with a supervised aerobic and resistance exercise program. Body composition will be assessed using dual energy X ray absorptiometry, while disease activity functional status muscle strength and inflammatory markers will be evaluated at baseline and at six months. The findings of this study may help clarify the role of exercise induced changes in adipose tissue in improving disease activity and overall functional status in rheumatoid arthritis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between eighteen and fifty years, either gender Diagnosed with rheumatoid arthritis according to the two thousand ten ACR EULAR classification criteria Disease duration between six months and five years Active disease with DAS twenty eight ESR greater than three point one On stable standard medical treatment for rheumatoid arthritis Willing to undergo dual energy X ray absorptiometry assessment Willing to participate in a six month structured aerobic and resistance exercise program Able to comply with study procedures and follow up assessments Written.
排除标准
- •Presence of any other autoimmune or systemic inflammatory disorder Uncontrolled medical conditions such as cardiovascular disease diabetes hypertension dyslipidemia or hypothyroidism Current or past history of malignancy Pregnant or lactating women Contraindication to dual energy X ray absorptiometry assessment Body mass index more than thirty five Any musculoskeletal neurological or cardiopulmonary condition limiting safe participation in exercise Inability or unwillingness to comply with study protocol.
研究者
Kanika Markan
Noida International University