JPRN-jRCTs051180080已完成2 期
Treatment of Neuromyelitis Optica with Mycophenolate Mofetil in Japanese Patients - An open treatment trial of NMO with MMF
Sekiguchi Kenji0 个研究点目标入组 9 人开始时间: 2019年2月27日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 9
研究概览
简要总结
MMF was effective for preventing relapse of neuromyelitis optica spectrum disorders with concomitant half dose oral corticosteroid reduction in 7/9 (77.8%, 95%CI (0.46%, 97.3%)) patients. MMF induction ameliorated cognitive tests scores without exacerbating EDSS scores. There were no cases of discontinuation of MMF due to adverse effects.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 < 80age old（—）
- 性别
- All
入选标准
- •Stable Neuromyelitis Optica patients with EDSS score less than 7.0 who wish to participate in this study
排除标准
- •1. Patients with infection
- •2. Patients with pregnancy or breast-feeding
- •3. Patients who take any immunosuppressant other than steroid
- •4. patients with severe liver or kidney dysfunction
- •5. patients with a history of cancer within 5 years (including carcinoma in situ)
- •6. In addition, patients judged inappropriate by the investigators
研究者
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