跳至主要内容
临床试验/CTRI/2025/07/091270
CTRI/2025/07/091270尚未招募不适用

To assess the right ventricular function using transesophageal echocardiogram before and after coronary ypass surgery

Cherry J B Kharbudnah1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年8月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To measure the right ventricular systolic function

研究概览

简要总结

Over the years the focus has shifted from Left ventricular to right ventricular function because of the growing evidence of Right ventricular Dysfunction following cardiac surgeries. Right ventricular dysfunction following cardiac surgery is associated with high mortality and morbidity. A decrease in RV function can occur during or immediately after cardiac surgery. Though the mechanism of RV dysfunction is not known, few studies have suggested impaired diastolic function of the right ventricle as one of the major cause of hemodynamic derangements observed during the surgery, other complications are related to poor right sided myocardial preservation with retrograde cardioplegia, increased afterload following cardiopulmonary bypass and air embolism during de airing in on pump coronary artery bypass graft surgery, while there are limited data on RV dysfunction in patients undergoing off pump coronary artery bypasss grafting surgery. Perioperative assessment of RV function is complex and achieved using different parameters. Though the qualitative assessment has good sensitivity it is less specific in terms of differentiation between normal and abnormal RV function. Guidelines of Echocardiographic assessment of Right Ventricle have suggested assessment of atleast FAC ( fractional Area Change), S’, TAPSE( tricuspid annular plane systolic excursion) with or without RV index of myocardial performance.Our study aims to assess change in RV systolic function during CABG surgery using following parameters TAPSE and FAC

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

To measure the right ventricular systolic function

时间窗: baseline

1. longitudinal measures of RV systolic function using TAPSE

时间窗: baseline

2. Global measures of RV systolic function using FAC

时间窗: baseline

次要结局

  • Requirement of vasopressor/ inotrope/ inodilator(Right ventricular failure)

研究者

发起方
Cherry J B Kharbudnah
申办方类型
Other [self financing]
责任方
Principal Investigator
主要研究者

Dr Cherry J B Kharbudnah

Sri Rmachandra Institute Of Higher Education and Research

研究点 (1)

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