Comparison of weaning from high flow nasal cannula versus direct transition to nasal prong oxygen therapy in children with respiratory distress-a randomized controlled trial.
Overview
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- JIPMER IMRF
- Enrollment
- 136
- Locations
- 1
- Primary Endpoint
- To compare the efficacy between weaning from high flow nasal cannula & direct transition from high flow nasal cannula to nasal prong oxygen therapy in terms of improvement in respiratory assessment score in managing children aged 1 month (corrected) to 5 years (completed)with respiratory distress
Overview
Brief Summary
Although there are several studies regarding high flow nasal cannula efficiency, there is no consensus on starting maintenance and weaning methods. A deeper understanding of HFNC weaning is essential. As unnecessary slow weaning may prolong hospital stay .They are only few studies regarding weaning strategy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 1.00 Month(s) to 5.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •All children aged one month to completed 5 years with clinical diagnosis of respiratory distress with respiratory assessment score of 6 or more.
Exclusion Criteria
- •Children with hemodynamic instability children who need mechanical ventilator support children with known/suspected heart disease children with known/suspected neuromuscular disorder children with suspected upper airway obstruction or foreign body children with suspected air leak children with suspected intestinal obstruction children receiving HFNC therapy via tracheostomy tube children received HFNC within 1 month children who weaned from mechanical ventilation to HFNC.
Outcomes
Primary Outcomes
To compare the efficacy between weaning from high flow nasal cannula & direct transition from high flow nasal cannula to nasal prong oxygen therapy in terms of improvement in respiratory assessment score in managing children aged 1 month (corrected) to 5 years (completed)with respiratory distress
Time Frame: To compare the efficacy between weaning from high flow nasal cannula & direct transition from high flow nasal cannula to nasal prong oxygen therapy in terms of improvement in respiratory assessment score in managing children aged 1 month (corrected) to 5 years (completed)with respiratory distress
Secondary Outcomes
- To compare the following between weaning from high flow nasal cannula & direct transition from high flow nasal cannula to nasal prong oxygen therapy in terms of improvement in respiratory assessment score in managing children aged 1 month (corrected) to 5 years (completed)with respiratory distress(to compare the need for invasive mechanical ventilation)
Investigators
Sisira C R
JIPMER