Images in Extracranial Artery Stenosis

• Conditions: Extracranial Atherosclerosis

• Registration Number: NCT00173927
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The goals of this trial are:

1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.

2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-03
• Status Verified: 2005-09
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-13
• Study First Posted: 2005-09-15
• Last Update Submitted: 2007-10-29
• Last Update Posted: 2007-10-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

Exclusion Criteria

• Acute systemic illness
• Creatinine > 3 mg/dl
• Unable to tolerate the tests (including MRI and PET/computed tomography [CT] scans)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan