Multicenter AIDS Cohort Study (MACS)
- Conditions
- HIV Infections
- Registration Number
- NCT00046280
- Brief Summary
This is a comprehensive observational study of HIV infection in homosexual and bisexual men.
- Detailed Description
The Multicenter AIDS Cohort Study (MACS) provides important information about the changing nature of HIV-mediated disease progression, the impact of antiretroviral treatment, the nature of HIV pathogenesis, and viral and host genetic factors. This study will also assess the long-term patterns of therapy use and risk-taking behaviors.
Patients will have study visits every 6 months. The visits will include interviews, specimen collection, and a physical examination.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 7087
- HIV negative, or
- HIV positive and no history or current use of highly active antiretroviral therapy (HAART), or
- HIV positive HAART recipient with documentation of HAART initiation, no AIDS diagnosis prior to HAART initiation, and a CD4 cell count and HIV-1 RNA measurement within 6 months prior to first HAART use.
- Sexual intercourse with men or at least 5 male or female partners in the 5 years prior to enrollment.
- Injection drug use within 1 year of enrollment.
- Perinatally acquired HIV infection.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (4)
Public Health Center
🇺🇸Los Angeles, California, United States
CORE Health Center
🇺🇸Chicago, Illinois, United States
Johns Hopkins School of Public Health
🇺🇸Baltimore, Maryland, United States
University of Pittsburgh School of Public Health
🇺🇸Pittsburgh, Pennsylvania, United States
Public Health Center🇺🇸Los Angeles, California, United States