The Effect of Exercise Timing on Postprandial Glycaemic Control: a Randomised Crossover Trial in Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 12
- 主要终点
- Postprandial glucose
研究概览
简要总结
Randomised crossover trial to compare early vs late walking on postprandial glycaemic response at night time.
详细描述
In this crossover trial, eligible participants will be randomised to a 30-minute bout of physical activity (30 minute walk) either during the day or after an evening meal. The postprandial response to the evening meal will be analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
盲法说明
This is a single masking study.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men and Women aged 18 to 65 years of age
- •Waist circumference of <94cm and <80cm for Caucasian males and females, respectively
- •Waist circumference of <90cm and <80 cm for Asian males and females, respectively
- •Willingness to provide written informed consent and willingness to participate and comply with the study
排除标准
- •Current or recent treatment (within 6 months) with medications that influence blood glucose
- •Fasting blood glucose ≥ 7 mmol/L
- •Individuals diagnosed with type 1 or type 2 diabetes mellitus, chronic gastrointestinal disorders (including inflammatory bowel disease and celiac) or any other condition deemed unstable
- •Serious health conditions that may affect participation e.g. liver or thyroid dysfunction, recent major surgery
- •Not able to walk for 30 mins at 5-5.5 km/hr
- •Women planning pregnancy, pregnant or lactating.
研究组 & 干预措施
Early exercise
Participants will exercise for 30 minutes prior to an evening meal
干预措施: Early exercise (Other)
Late exercise
Participants will exercise for 30 minutes after an evening meal
干预措施: Late exercise (Other)
结局指标
主要结局
Postprandial glucose
时间窗: Three hour glucose iAUC will be calculated at nine time points (0, 15, 30, 45, 60, 90, 120, 150 and 180 mins) after beginning consumption of the test meal.
Change in glucose incremental area under the curve (iAUC) in response to a meal challenge
次要结局
- Postprandial insulin(Three hour insulin iAUC will be calculated at six time points (0, 30, 60, 90, 120 and 180 mins) after beginning consumption of the test meal.)