Natural History and Nonoperative Management of Penetrating Cerebrovascular Injury
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- number of patients with stroke
研究概览
简要总结
The goal of this study is to evaluate a series of cases of penetrating cerebrovascular injury managed without upfront operation. Investigators focus on patient characteristics, injury details, treatment modalities, serial imaging studies, patient outcomes, and complications. Investigators will compare this patient population to patients managed with upfront operation for context.
详细描述
Penetrating cerebrovascular injuries (PCVIs) are uncommon, with little data to guide management when emergent operative repair is not performed. Investigators hypothesized that PCVIs may be managed with antithrombotic therapy and directed use of endovascular interventions, but that PCVIs may require enhanced surveillance due to a risk of delayed complications. To perform this study, investigators will review patients with penetrating carotid and vertebral artery injuries managed at an urban Level I trauma center from 2016 to 2022. Patients will be included if they underwent initial nonoperative management (NOM). Patient characteristics, injury details, treatments, serial imaging, outcomes, and complications will be assessed in a retrospective manner using chart abstraction. Investigators will briefly compare these patients to those managed with upfront operations for context.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Penetrating neck trauma
- •Carotid or vertebral artery injury
排除标准
- 未提供
结局指标
主要结局
number of patients with stroke
时间窗: up to one year post-injury
ischemic stroke
次要结局
- number of patients with bleeding complications(up to one year post-injury)
- number of patients with death(up to one year post-injury)
- number of patients with injury progression(up to one year post-injury)
- number of patients treated with operative exploration(up to one year post-injury)
- number of patients treated with arterial embolization or arterial stent placement(up to one year post-injury)
研究者
Cordelie Witt
Investigator
Poudre Valley Health System