Management strategies for Chinese women with gestational diabetes

Not Applicable

Completed

• Conditions: Gestational diabetes mellitus; Pregnancy and Childbirth

• Registration Number: ISRCTN40260907
• Lead Sponsor: Guangxi Natural Science Foundation

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-03-15
• Study Start: 2024-06-17
• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 184

Inclusion Criteria

1. Pregnant women with GDM at 24–28 weeks of gestation. A diagnosis of GDM is made using the one-step approach of a 75-g oral glucose tolerance test if the plasma glucose value is abnormal (i.e., fasting blood glucose =5.1 mmol/L, 1 hour =10.0 mmol/L, 2 hours =8.5 mmol/L)
2. Single pregnancy
3. Body mass index (BMI) <40 kg/m2
4. Muscle strength at level IV or above

Exclusion Criteria

1. Severe obstetric complications and contraindications listed in the public health guidelines for physical activity during pregnancy
2. Severe heart, liver, lung, or kidney damage
3. Acute or chronic complications caused by diabetes, such as ketoacidosis or diabetic foot

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Fasting blood glucose (FBG) measured using glucose oxidase method<br>2. 2-hour postprandial blood glucose (2h-PBG) measured using glucose oxidase method<br>3. Glycated hemoglobin (HbA1c) measured using high-performance liquid chromatography (HPLC)<br><br>Data collection was conducted at the baseline before the intervention, 1 and 3 months after the intervention, and 2 hours after the delivery

Secondary Outcome Measures

Name	Time	Method
1. Maternal pregnancy outcomes: gestational age, preterm birth, mode of delivery, gestational hypertension syndrome, insulin use, late pregnancy weight gain, postpartum hemorrhage measured using patients’ medical records<br>2. Neonatal birth outcomes: birth weight, length at birth, 1-minute Apgar score, and incidence of neonatal complications such as respiratory distress syndrome measured using patients’ medical records<br><br>Data collection was conducted at the baseline before the intervention, 1 and 3 months after the intervention, and 2 hours after the delivery