Influenza IMPRINT Cohort: Defining the Impact of Initial Influenza Exposure on Immunity in Infants
- Conditions
- Influenza
- Registration Number
- NCT05436184
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1500
Inclusion Criteria:<br><br> - Mother pregnant and = 34 weeks gestation and = 18 yrs. of age<br><br> - Plans to deliver at local hospital<br><br> - Lives within designated home zip codes:<br><br> - No plans to move outside study area within study timeframe<br><br> - Cell phone that can be used for text messaging<br><br> - Singleton live born infant, born = 34 weeks gestational age (GA)<br><br>Exclusion Criteria:<br><br> - Fetal or infant death prior to maternal hospital discharge<br><br> - Mother known to be infected with HIV based on medical records<br><br> - Major congenital anomalies, prenatally diagnosed or other major disorder or anomaly<br> as determined by the PI<br><br> - Reported use of heroin, cocaine or methamphetamines during pregnancy<br><br> - Adoptive infant<br><br> - Enrolled in any investigational vaccine trial or other interventional randomized,<br> clinical trial involving the mother or infant that the PI's deem to be in conflict<br> with study outcomes
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immune response to influenza virus infection;Immune response to influenza vaccination
- Secondary Outcome Measures
Name Time Method