A clinical trial to study the role of dexmedetomidine to control shivering after operation of head.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Patients undergoing craniotomy
- Registration Number
- CTRI/2018/04/012921
- Lead Sponsor
- Bangur Institute of Neurosciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 76
Inclusion Criteria
1)Written informed consent of the patients.
2)ASA grade I and II.
3)Age between 18 â?? 60 years.
4)Patients of either sex.
5)Patients scheduled for craniotomy operations who are supposed to be operated within 3 hours.
Exclusion Criteria
1)Patientsâ?? refusal.
2)ASA grade III and IV.
3)Patients allergic to study medications.
4)Patientsâ?? with thyroid disorder, Parkinsons disease, dysautonomia, Raynaudâ??s syndrome, cardiopulmonary disease, history of allergy to drugs used, history of chronic use of sedative and hypnotic drugs.
i)History of conduction defect of heart.
ii)Initial core temperature >37.5oC or <36.5oC.
iii)Obese patients with B.M.I >30.
iv)Pregnant or lactating women.
v)Renal or hepatic dysfunction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of patients suffered from post-operative shivering in each group.Timepoint: first 6 hr postoperative
- Secondary Outcome Measures
Name Time Method 1)Number of patients required rescue drug for shivering in the post-operative period. <br/ ><br>2)postoperative sedation <br/ ><br>3)intra operative blood pressure and heart rate <br/ ><br>4)any side effects like hypotension,bradycardia,nausea postoperativelyTimepoint: first 6 hr postoperative