Effect of perioperative Dexmedetomidine infusion on blood glucose levels in non diabetic morbid obese patients undergoing laparoscopic bariatric surge
Not Applicable
- Conditions
- Surgery
- Registration Number
- PACTR201604001510193
- Lead Sponsor
- Raham Hasan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
ASA physical status II and III
of either sex
aged 20-50 years
BMI ranging from 35-55 kg/m2
Exclusion Criteria
cardiac, pulmonary, hepatic, renal, or metabolic disorders
receiving medications that might affect sympathetic response or hormonal secretions.
Also, none have other Endocrine disorders that affect blood glucose levels such as Cushing syndrome and Hyperthyroidism or are receiving drug therapy significantly affecting blood glucose level such as Corticosteroid therapy.
Patients with history of allergy to the study drugs, therapy with vasoactive medications or positive pregnancy test were excluded from the study
Also, patients with allergy to eggs or soy were excluded.
Complicated surgeries of more than 2 h were also excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method investigate the influence of dexmedetomidine premedication on modulation of neuroendocrine stress response during laparoscopic bariatric surgery under general anesthesia by analyzing the variation of perioperative serial blood glucose levels
- Secondary Outcome Measures
Name Time Method All patients were also assessed for intraoperative hemodynamic changes of heart rate and mean arterial pressure at specific timings, intraoperative sevoflurane requirements and narcotic consumption.