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临床试验/NCT00691535
NCT00691535已完成不适用

Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression

Stanford University1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2003年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
500
试验地点
1

研究概览

简要总结

We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.

详细描述

From the blood sample you donate, the researchers will obtain DNA. This DNA will be used to search for DNA markers related to the underlying biology of psychiatric illness and how this might explain the symptoms of these disorders. Research using DNA is an important way to try to understand human disease and/or the role genes play in disease. In effect, part of your blood sample will be used to attempt to understand how genetic factors contribute to the symptoms of such psychiatric conditions as major depression.

研究设计

研究类型
Observational
时间视角
Other

入排标准

性别
All
接受健康志愿者

入选标准

  • You are currently experiencing symptoms that are consistent with an episode of major depression without symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  • You are currently experiencing symptoms that are consistent with an episode of major depression with symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
  • You have been diagnosed with either schizophrenia or schizoaffective disorder, or
  • You are a volunteer without a history of psychiatric illness (a healthy control subject).

排除标准

  • 未提供

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alan Schatzberg

Principle Investigator

Stanford University

研究点 (1)

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