Transcranial Doppler and Neurological Complications After Liver Transplantation

Mansoura University1 site in 1 country100 target enrollmentNovember 28, 2021

ConditionsLiver Transplantation Ultrasonography, Doppler, Transcranial Complication, Postoperative Neurologic Deficits

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Liver Transplantation
Sponsor: Mansoura University
Enrollment: 100
Locations: 1
Primary Endpoint: Post-transplant Neurological Complication
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a prospective study that would investigate the transcranial doppler (TCD) changes during the living donor liver transplantation and the association between the TCD changes and the post-transplant neurological complications.

Detailed Description

Objectives: Participants \& Setting: Intervention \& Measurements: Sample size:

Registry

clinicaltrials.gov

Start Date

November 28, 2021

End Date

April 28, 2024

Last Updated

4 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Mansoura University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•all patients scheduled for living donor liver transplantation for whatever the indication at Gastrointestinal surgery center (GISC)

Exclusion Criteria

•Patients with coexisting neuropsychiatric or cerebrovascular disorders or those who have a history of head trauma or brain surgery

Outcomes

Primary Outcomes

Post-transplant Neurological Complication

Time Frame: 28 days after transplantation

incidence of Neurological Complication as a composite outcome (tremors, seizures, demyelination, posterior reversible encephalopathy syndrome, stroke)