NCT05144451
Unknown
N/A
Transcranial Doppler and Neurological Complications After Liver Transplantation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Liver Transplantation
- Sponsor
- Mansoura University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Post-transplant Neurological Complication
- Last Updated
- 4 years ago
Overview
Brief Summary
This is a prospective study that would investigate the transcranial doppler (TCD) changes during the living donor liver transplantation and the association between the TCD changes and the post-transplant neurological complications.
Detailed Description
Objectives: Participants \& Setting: Intervention \& Measurements: Sample size:
Investigators
Eligibility Criteria
Inclusion Criteria
- •all patients scheduled for living donor liver transplantation for whatever the indication at Gastrointestinal surgery center (GISC)
Exclusion Criteria
- •Patients with coexisting neuropsychiatric or cerebrovascular disorders or those who have a history of head trauma or brain surgery
Outcomes
Primary Outcomes
Post-transplant Neurological Complication
Time Frame: 28 days after transplantation
incidence of Neurological Complication as a composite outcome (tremors, seizures, demyelination, posterior reversible encephalopathy syndrome, stroke)
Secondary Outcomes
- flow patterns throughout the transplant surgery and in the ICU(intraoperative and 7 days after transplantion)
Study Sites (1)
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