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临床试验/NCT05144451
NCT05144451Unknown不适用

Transcranial Doppler and Neurological Complications After Liver Transplantation

Mansoura University2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年11月28日最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
试验地点
2
主要终点
Post-transplant Neurological Complication

研究概览

简要总结

This is a prospective study that would investigate the transcranial doppler (TCD) changes during the living donor liver transplantation and the association between the TCD changes and the post-transplant neurological complications.

详细描述

Objectives:

Participants & Setting:

Intervention & Measurements:

Sample size:

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • all patients scheduled for living donor liver transplantation for whatever the indication at Gastrointestinal surgery center (GISC)

排除标准

  • Patients with coexisting neuropsychiatric or cerebrovascular disorders or those who have a history of head trauma or brain surgery

结局指标

主要结局

Post-transplant Neurological Complication

时间窗: 28 days after transplantation

incidence of Neurological Complication as a composite outcome (tremors, seizures, demyelination, posterior reversible encephalopathy syndrome, stroke)

次要结局

  • flow patterns throughout the transplant surgery and in the ICU(intraoperative and 7 days after transplantion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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