Evaluation of the metabolic profile of saliva and plasma associated with Periodontitis in obese and eutrophic pregnant women and of proteins differentially expressed in the saliva of these women in pre and post term

Faculdade de Odontologia de Bauru - Universidade de São Paulo0 个研究点开始时间: 2022年9月23日最近更新: 2023年5月29日

适应症

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•Pregnant women aged 18–40 years; who were in the 3rd trimester of pregnancy, between 27th and 39th gestational weeks; with regular follow-up with the obstetrician; and who had adequate cognitive function during pregnancy, without impairments that required absolute rest

•Twin pregnancy; individuals with neuromotor impairment; arterial hypertension during pregnancy; Gestational Diabetes Mellitus; malnutrition; overweight, therefore, BMI between 25.00 and 29.99 kg/m2; confirmed or suspected diagnosis of SARS-CoV-2 infection; with hyposalivation; subjects who were using or who used at some point in pregnancy antibiotics or any medication that could interfere with periodontal status and/or salivary flow, e.g., immunosuppressive, anticonvulsant or calcium channel-blocking drugs, such as cyclosporine, phenytoin or nifedipine, respectively; who were under orthodontic treatment or any dental treatment with another professional; participants with cavitated caries lesions; with severe dental wear; with diagnosis of stages I and IV of periodontitis; with multiple tooth loss, being more than two teeth per hemiarch; with self-reported systemic disease besides obesity; and users of alcohol, tobacco, or illicit drugs

发起方

Faculdade de Odontologia de Bauru - Universidade de São Paulo