Evaluation of the metabolic profile of saliva and plasma associated with Periodontitis in obese and eutrophic pregnant women and of proteins differentially expressed in the saliva of these women in pre and post term

Faculdade de Odontologia de Bauru - Universidade de São Paulo0 个研究点开始时间: 2022年9月20日最近更新: 2023年5月29日

适应症

试验速览

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•Be between 18 and 40 years old; during the 3rd trimester of pregnancy, between the 27th and 39th gestational week; with regular follow-up with the obstetrician; with adequate cognitive function during pregnancy; with no problem that required absolute rest

•Twin pregnancies; individuals with neuromotor impairments; arterial hypertension during pregnancy; Gestational Diabetes Mellitus; malnutrition; overweight, therefore, body mass index between 25.00 and 29.99 kg/m2; confirmed or suspected diagnosis of SARS-CoV-2 infection; hyposalivation; subjects who were using or who used at some point in pregnancy antibiotics or any medication that could interfere with periodontal status or salivary flow, e.g. immunosuppressive drugs, anticonvulsants or calcium channel blockers; who were under orthodontic treatment or any dental treatment with another professional; with multiple tooth loss, so more than two teeth per hemiarch; self-reported systemic disease besides obesity; and users of alcohol, tobacco, and illicit drugs

发起方

Faculdade de Odontologia de Bauru - Universidade de São Paulo