comparison of two adjuvant drugs to prolong spinal anaesthesia

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/09/045923
• Lead Sponsor: JNUIMSRC

Brief Summary

60 patients posted for orthopedic surgery of lower limbs under spinal anaesthesia will be studied to compare the effects of intrathecal dexmedetomidine with hyperbaric bupivacaine and intrathecal nalbuphine with hyperbaric bupivacaine.

The study will comprise of 2 groups of 30 patients each of ASA  grade 1 and 2 status.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-09-23
• Study Start: 2022-09-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA 1 and 2.

Exclusion Criteria

Bleeding diathesis local infection severe systemic diseases spinal deformities and surgery not willing to give consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
onset of sensory and motor blocks	onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia
duration of sensory and motor blocks	onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia
duration of analgesia	onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia

Secondary Outcome Measures

Name	Time	Method
any side effects	every 30 minutes

Trial Locations

Locations (1)

JNUIMSRC; 🇮🇳 Jaipur, RAJASTHAN, India

JNUIMSRC

🇮🇳Jaipur, RAJASTHAN, India

Dr Geetanjali Singhal

Principal investigator

9829051344

singhalgeetanjali@yahoo.com