A Comparison between Intrathecal Nalbuphine and Intrathecal Dexmedetomidine as adjuvant to 0.5% hyperbaric bupivacaine for orthopedic surgery of lower limbs under Sub Arachnoid Block
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- onset of sensory and motor blocks
研究概览
简要总结
60 patients posted for orthopedic surgery of lower limbs under spinal anaesthesia will be studied to compare the effects of intrathecal dexmedetomidine with hyperbaric bupivacaine and intrathecal nalbuphine with hyperbaric bupivacaine.
The study will comprise of 2 groups of 30 patients each of ASA grade 1 and 2 status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 25.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1 and 2.
排除标准
- •Bleeding diathesis local infection severe systemic diseases spinal deformities and surgery not willing to give consent.
结局指标
主要结局
onset of sensory and motor blocks
时间窗: onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia
duration of sensory and motor blocks
时间窗: onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia
duration of analgesia
时间窗: onset of sensory and motor blocks at 2, 4, 6, and 8 minutes | Duration of analgesia at 2, 3, 4, and 5 hours | duration of sensory and motor blocks at 60, 90, 120, 150, and 180 minutes | duration of analgesia
次要结局
- any side effects(every 30 minutes)