Thrombus characterization using MRI in intermediate-high-risk patients with pulmonary embolism and catheter-based interventional treatment

• Conditions: I26.0; Pulmonary embolism with mention of acute cor pulmonale

• Registration Number: DRKS00032538
• Lead Sponsor: Klinikum rechts der Isar der Technischen Universität München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1.) Age from 18 years up to and including 85 years
2.) Confirmed acute pulmonary artery embolism using CTPA (computed tomographic pulmonary angiography)
3.) Diameter ratio between right and left ventricles (RV/LV) = 1 in CT scan or echocardiography
4.) Concentration of troponin T above the detection limit
5.) PESI Score III-V

Exclusion Criteria

1.) Hemodynamic instability
2.) Pregnancy or breastfeeding
3.) Low-risk pulmonary artery embolism
4.) Earlier inclusion in the study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Thrombus age depending on the T1 relaxation time in MRI and histology

Secondary Outcome Measures

Name	Time	Method
RV/LV ratio, TAPSE, oxygen saturation, blood pressure, heart rate