Electrical Impedance Tomography during Flow Controlled Ventilation in the Intensive Care Unit
- Conditions
- Atelectraumalung collapse10024967
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
- The subject is 18 years or older
- Informed consent form is signed by the subject or a legal representative
- Controlled mechanical ventilation via an endotracheal tube
- Severe sputum stasis or production requiring frequent bronchial suctioning
(more than 5 times per nurse shift)
- Severe respiratory insufficiency defined as a PaO2 to FiO2 ratio of <100mmHg
or moderate to severe ARDS according to the Berlin definition for ARDS
- Untreated pneumothorax (i.e. no pleural drainage)
- Hemodynamic instability defined as a mean arterial pressure below 60mmHg not
responding to fluids and/or vasopressors
- Excessive subcutaneous emphysema (prevents proper functioning of the EIT
device)
- Thoracic wounds, bandages or other obstruction which prevent proper
functioning of the EIT device
- High (>15 mmHg) or instable (requiring more sedation or osmotherapy)
intracranial pressure
- An inner tube diameter of 6mm or less
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoints of this study are lung volume measured by EIT and minute<br /><br>volume measured by the ventilator during either FCV or CMV at the ICU.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints of this study are a comparison of:<br /><br>- Airway pressures (peak airway pressure, mean airway pressure, PEEP) between<br /><br>FCV and CMV.<br /><br>- Lung aeration score with ultrasound between FCV and CMV<br /><br>- Hemodynamic parameters (e.g. mean arterial pressure, heart rate, dose of<br /><br>vasopressors, urine production) between FCV and CMV<br /><br>- Dissipated energy between FCV and CMV<br /><br>- Safety of FCV</p><br>