MedPath

Pain Management in Osteoarthritis through Homoeopathy

Phase 3
Conditions
Health Condition 1: null- Osteoarthritis
Registration Number
CTRI/2014/02/004372
Lead Sponsor
Central Council for Research in Homoeopathy
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
200
Inclusion Criteria

Patients above the age of 50 years, presenting with knee pain and evidence of osteophytes in the knee radiograph

Exclusion Criteria

•Rheumatoid factor more than 1:40 titre

•ESR more than 40mm/hour

•Serum uric acid level >7 mg/dL in men or >6 mg/dL in women

•Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( > 12°); evidenced by imaging or other evidences and requiring surgical intervention

•Non-ambulant patients

•Self-reported joint disorders (e.g. inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) other than OA

•IA injections within 2 weeks prior to study entry

•Cases with other systemic unevaluated or uncontrolled diseases like diabetes mellitus, hypertension, or other cardiovascular, renal, gastro-intestinal, endocrinal, gynecological diseases etc. or systemic infections affecting quality of life or on other treatment therapies

•Psychiatric illness

•Patients with any vital organ failure

•Recent knee surgery within last 6 months

•Cases with transplanted knees

•History of homeopathic treatment for any chronic disease within last 6 months

•Self-reported immune-compromised states

•Alcohol and/or drug addiction or dependence

•Cases with controlled/uncomplicated hypertension, diabetes mellitus, etc. will not be excluded. Patients on life-saving conventional drug therapies, e.g. anti-diabetics, anti-hypertensives, thyroid drugs etc. for co-morbidities under control, will be continued.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in pain, stiffness, limitation of movement on an identified scale <br/ ><br>Change in pain measured on identified scale (OARSI - OMERACT constant/intermittent pain measure)Timepoint: every 15 days till 2 months of treatment
Secondary Outcome Measures
NameTimeMethod
Change in requirement of NSAIDs during the course of treatment <br/ ><br>â?¢Incidence of any adverse events/severe adverse events during the period of treatmentTimepoint: every 15 days till 2 months of treatment
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