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临床试验/NCT03566901
NCT03566901
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Robot-assisted Locomotor and Stair Climbing Training for Improving Mobility and Participation in Daily Activities in Persons Affected by Stroke: a Multicenter Randomized Controlled Clinical Trial

Universita di Verona2 个研究点 分布在 1 个国家目标入组 72 人2017年10月1日
适应症Stroke

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Stroke
发起方
Universita di Verona
入组人数
72
试验地点
2
主要终点
The time required to climb Up and Down 9 stairs (seconds)
最后更新
7年前

概览

简要总结

Stair climbing up and down is an essential part of everyday's mobility. Physiotherapy is focused on muscle strengthening, real floor walking and stairs climbing tasks, but these methods do not stress in terms of intensity stair-climbing practice. The aims of this study is to compare whether an intensive robot-assisted stair climbing training (RASCT) is more effective than conventional physiotherapy (CP) for improving stair climbing ability, gait and postural control in stroke patients.

详细描述

Trial design: A pilot randomized (allocation ratio 1:1), single blind clinical trial (RCT) comparing the effects between the experimental \[Robot-Assisted Stair Climbing Training group (RASCT)\] and control group (Conventional Physiotherapy, CP) in improving stair climbing ability and postural control in stroke patients. The examiner will be blind to group assignment.

注册库
clinicaltrials.gov
开始日期
2017年10月1日
结束日期
2018年11月1日
最后更新
7年前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

发起方
Universita di Verona
责任方
Principal Investigator
主要研究者

Nicola Smania, MD, Clinical Professor

Professor of Rehabilitation Medicine

Universita di Verona

入排标准

入选标准

  • First-ever ischemic or hemorrhagic stroke;
  • More than or equal to 3 months post stroke;
  • Age\>18 years;
  • Mini- Mental State Examination (MMSE) score more than 23;
  • Ability to stand for at least 1 min without arm support; ability to walk independently for at least 10 m with or without walking aids;
  • Functional Ambulation Category score equal or more than
  • Signed informed consent form

排除标准

  • Severe cognitive or communicative disorders that hamper collaboration;
  • Unstable cardiovascular system conditions (i.e. labile compensated cardiac insufficiency, angina pectoris), deep vein thrombosis, severe neurological or orthopedic diseases which massively affect lower limb mobility; severe joint misalignment;
  • Treatment of lower limb spasticity (i.e. botulinum toxin) in the 3 months prior to the start of the study and/or during its execution.

结局指标

主要结局

The time required to climb Up and Down 9 stairs (seconds)

时间窗: 1 day

(seconds)

次要结局

  • 6-Minute Walking Test evaluates walking endurance.(1 day)
  • Fatigue Severity Scale(1 day)
  • Barthel Index(1 day)
  • EMG gait(1 day)
  • The Timed Up and Go test evaluates person's mobility.(1 day)
  • The Modified Ashworth Scale evaluates muscle spasticity.(1 day)
  • Borg Scale(1 day)
  • Stabilometric assessment(1 day)
  • The 10-Meter Walking Test evaluates gait speed.(1 day)
  • Functional Ambulation Category (FAC);(1 day)
  • Dynamic Gait Index (DGI)(1 day)
  • European Stroke Scale(1 day)
  • Blood pressure(1 day)
  • The Berg Balance Scale evaluates standing balance during functional activities.(1 day)
  • Number of steps performed with the Robot and without.(1 day)
  • heart beat(1 day)

研究点 (2)

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