Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulatio
Not Applicable
- Conditions
- Patients under 18 years old who were administered intravenous vancomycin in Department of Pediatrics or Department of Pediatric Cardiology in our institute between April 1st 2011 and March 31st 2016.
- Registration Number
- JPRN-UMIN000022343
- Lead Sponsor
- Department of Pediatrics, Yokohama City University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with renal dysfunction. Data unavailability exists. Lack of informed consent.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The proportion of the patients who achieved more than 400 of AUC/MIC in the present treatment strategy in our institute.
- Secondary Outcome Measures
Name Time Method To compare the duration required for body temperature to be normalized between the populations with AUC/MIC above 400 and below 400. With Monte Carlo simulation, we will optimize the treatment strategy of vancomycin so that more than 90% of the patients achieve AUC/MIC more than 400.