Effect of Wheat Dextrin on Calcium and Magnesium Absorption
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Creighton University
- Enrollment
- 40
- Primary Endpoint
- Calcium Absorption
Study Overview
Brief Summary
To compare calcium and magnesium absorption within subjects with and without chronic consumption of wheat dextrin.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 19 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Subjects will be generally healthy Caucasian females aged 19 and older with no known abnormalities of gastrointestinal function, and taking no medications that might alter absorptive performance. BMI will be between 19 and 31 kg/m2
Exclusion Criteria
- Not provided
Arms & Interventions
placebo
Control cookies will contain no wheat dextrin and will be taken 3 times daily for 2 weeks.
Intervention: placebo (Dietary Supplement)
wheat dextrin
wheat dextrin (formulated according to the supporter's established method), will be baked in cookies providing three doses per day (≈5 gram of wheat dextrin in each dose)for 2 weeks.
Intervention: wheat dextrin (Dietary Supplement)
Outcomes
Primary Outcomes
Calcium Absorption
Time Frame: within 2-4 weeks
The calcium load to be tested will be 300 mg calcium from calcium and vitamin D fortified TropicanaTM orange juice extrinsically labeled with ≈3-7 μCi of 45Ca. The labeled orange juice will be ingested as part of a light meal, served as breakfast, after an overnight fast.
Secondary Outcomes
- Magnesium absorption(within 2-4 weeks)