CREIGHTON UNIVERSITY

Ensysce Biosciences Pioneers Novel Opioids with Built-in Overdose Prevention Technology

- Ensysce Biosciences has developed chemically modified oxycodone that remains inactive unless taken orally, significantly reducing abuse potential while maintaining pain relief efficacy. - The innovative technology includes built-in overdose protection mechanisms that prevent drug release when excessive doses are taken, addressing a critical safety concern in pain management. - The FDA has granted both Fast Track and Breakthrough Therapy designations to Ensysce's modified oxycodone, recognizing the urgent medical need for safer opioid alternatives.