Characterization of Impact of Urbanicity on Genetics, Cerebral functioning and –structure and Condition in Young people (URGENCY)

Recruiting

• Conditions: Impact of environment and kinesic behavior on genetic factors, brain structure and function and condition in people from young age onwards and possible development of psychiatric disorders

• Registration Number: DRKS00016671
• Lead Sponsor: Zentralinstitut für Seelische Gesundheit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-02-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Sufficient level of German or Arabic language; Ability to understand the study protocol and to give an informed consent; Will to use the device for ambulatory assessment

Exclusion Criteria

General exclusion criteria:
1) Subjects who spent most parts of their days outside of the target area (target areas are for example municipal district: Mannheim, Heidelberg und Ludwigshafen; administrative distric: Rhein-Neckar-Kreis/most parts of their days means: habitation of a secondary residence, school/work place or facilities visited [Auspendler], current location outside the target region, short stays outside the target area for two or more days per week)
2) chronic endocrinological, cardiovascular, immunological und clinically manifest psychiatric disorder
3) acute diseases

Exclusion criteria for MRI
1) regular intake of medicaments containing glucocorticoids
2) Drug abuse
3) Pregnancy
4) objects from metal in head or body (e.g. vascular clamps, metal prostheses, artificial heart valves, tiling, nails, wires, shrapnel, medication pump or other implants)
5) operation of heart or brain in medical history
6) therapeutic patches (nicotine, hormone, or against pain)
7) epilepsy
8) piercings which are not removable
9) Accident with unconsciousness in medical history
10) Claustrophobia

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ongitudinal study to search for epidemiological factors and investigate the impact of the environment, stress and functional and structural brain development.<br>All participants should attend three times for an MRI-testing to investigate long-term modifications.