The impact of the urban environment on spatial navigation in elderly subjects with mild cognitive impairment (UrbanNavMCI)

niversity of Lisbon0 个研究点目标入组 50 人开始时间: 2022年7月26日最近更新: 2022年10月24日

试验速览

暂无简介。

•1. This study will adopt the Petersen et al. (1999) criteria for the diagnosis of MCI (probably one of the original criteria defined) which include:
•1.1. Presence of memory complaints (from patients or their families)
•1.2. No or a minimal impairment in activities of daily living, determined by the Instrumental Activities of Daily Living Scale (IADL) (Lawton & Brody, 1969)
•1.3. Normal general cognitive function, determined by the Mini-Mental State Examination (MMSE) (Folstein, Folstein, & McHugh, 1975)
•1.4. An objective cognitive disorder as evidenced by a neuropsychological evaluation
•1.5. Absence of dementia
•2. Written informed consent
•3. The diagnosis of MCI will also be made by an experienced neurologist, using all available clinical, neuropsychological, and neuroimaging information available from the diagnostic workup

•1. Neurological (stroke, brain tumour, significant head trauma, epilepsy) or psychiatric disorders that may cause cognitive impairment
•2. Patients with major depression or serious depressive symptoms
•3. History of alcohol abuse or recurrent substance abuse or dependence
•4. Seriously reduced vision or other sensory deficits likely to interfere with the evaluation
•5. Medication use with possible cognitive side effects
•6. Presence of a systemic illness with significant cerebral impact (uncontrolled hypertension, metabolic, endocrine, toxic, and infectious diseases)

发起方

niversity of Lisbon